GSK3B, glycogen synthase kinase 3 beta, 2932

N. diseases: 393; N. variants: 25
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1154595
rs1154595 		3 120017747 intron variant C/T snv 0.53
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure 		0.700 1.000 1 2019 2019
dbSNP: rs1189501362
rs1189501362 		0.882 0.120 3 119863583 missense variant G/A snv 7.0E-06
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2003 2003
dbSNP: rs1189501362
rs1189501362 		0.882 0.120 3 119863583 missense variant G/A snv 7.0E-06
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2003 2003
dbSNP: rs1189501362
rs1189501362 		0.882 0.120 3 119863583 missense variant G/A snv 7.0E-06
CUI: C0949664
Disease: Tauopathies
Tauopathies 		Nervous System Diseases 0.010 1.000 1 2003 2003
dbSNP: rs1189501362
rs1189501362 		0.882 0.120 3 119863583 missense variant G/A snv 7.0E-06
CUI: C0338451
Disease: Frontotemporal dementia
Frontotemporal dementia 		Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders 0.010 1.000 1 2003 2003
dbSNP: rs12630592
rs12630592 		0.851 0.080 3 120049399 intron variant G/A;T snv
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 1.000 1 2017 2017
dbSNP: rs12630592
rs12630592 		0.851 0.080 3 120049399 intron variant G/A;T snv
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs12630592
rs12630592 		0.851 0.080 3 120049399 intron variant G/A;T snv
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.010 1.000 1 2017 2017
dbSNP: rs12630592
rs12630592 		0.851 0.080 3 120049399 intron variant G/A;T snv
CUI: C0154409
Disease: Recurrent major depressive episodes
Recurrent major depressive episodes 		Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs12630592
rs12630592 		0.851 0.080 3 120049399 intron variant G/A;T snv
CUI: C0338831
Disease: Manic
Manic 		Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs13320980
rs13320980 		1.000 0.040 3 119890313 intron variant T/C snv 0.23
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs13321783
rs13321783 		1.000 0.040 3 119896528 intron variant T/C snv 0.56
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs140442947
rs140442947 		1.000 0.080 3 119865430 intron variant T/C snv 5.9E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.700 1.000 1 2018 2018
dbSNP: rs16830551
rs16830551 		3 119834031 intron variant C/T snv 2.4E-02
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.700 1.000 1 2012 2012
dbSNP: rs16830551
rs16830551 		3 119834031 intron variant C/T snv 2.4E-02
CUI: C0428472
Disease: Serum HDL cholesterol measurement
Serum HDL cholesterol measurement 		0.700 1.000 1 2012 2012
dbSNP: rs16830551
rs16830551 		3 119834031 intron variant C/T snv 2.4E-02
CUI: C0428474
Disease: Serum LDL cholesterol measurement
Serum LDL cholesterol measurement 		0.700 1.000 1 2012 2012
dbSNP: rs16830551
rs16830551 		3 119834031 intron variant C/T snv 2.4E-02
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.700 1.000 1 2012 2012
dbSNP: rs1732170
rs1732170 		1.000 0.040 3 119864829 intron variant T/A;C snv
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1870931
rs1870931 		3 120038166 intron variant C/G snv 0.24
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs2199503
rs2199503 		0.851 0.080 3 120059642 intron variant T/C snv 0.79
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		Mental Disorders 0.010 1.000 1 2015 2015
dbSNP: rs2199503
rs2199503 		0.851 0.080 3 120059642 intron variant T/C snv 0.79
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.010 1.000 1 2017 2017
dbSNP: rs2199503
rs2199503 		0.851 0.080 3 120059642 intron variant T/C snv 0.79
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2015 2015
dbSNP: rs2199503
rs2199503 		0.851 0.080 3 120059642 intron variant T/C snv 0.79
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.010 1.000 1 2015 2015
dbSNP: rs2319398
rs2319398 		1.000 0.040 3 119894095 intron variant C/A snv 0.54
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs334535
rs334535 		0.882 0.040 3 120073457 intron variant C/T snv 0.29
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.010 1.000 1 2015 2015