HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.100 0.800 10 2010 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder 		Mental Disorders 0.060 0.833 6 2007 2018
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		Mental Disorders 0.050 1.000 5 2010 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.030 0.667 3 2014 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.030 1.000 3 2017 2017
dbSNP: rs7997012
rs7997012 		0.807 0.080 13 46837850 intron variant A/G snv 0.69
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.030 1.000 3 2011 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.020 1.000 2 2006 2018
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2011 2017
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		Mental Disorders 0.020 1.000 2 2014 2014
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2009 2014
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms 		Behavior and Behavior Mechanisms 0.020 1.000 2 2013 2014
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0033860
Disease: Psoriasis
Psoriasis 		Skin and Connective Tissue Diseases 0.020 1.000 2 2010 2020
dbSNP: rs7997012
rs7997012 		0.807 0.080 13 46837850 intron variant A/G snv 0.69
CUI: C0270549
Disease: Generalized Anxiety Disorder
Generalized Anxiety Disorder 		Mental Disorders 0.020 1.000 2 2013 2013
dbSNP: rs12584920
rs12584920 		1.000 0.040 13 46890902 intron variant G/C;T snv
CUI: C3178789
Disease: Widespread Chronic Pain
Widespread Chronic Pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2011 2011
dbSNP: rs1328674
rs1328674 		1.000 0.120 13 46867572 intron variant T/C;G snv
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1475196
rs1475196 		1.000 0.040 13 46881488 intron variant A/C snv 1.4E-03
CUI: C0853193
Disease: Bipolar I disorder
Bipolar I disorder 		Mental Disorders 0.010 1.000 1 2014 2014
dbSNP: rs17069005
rs17069005 		1.000 0.080 13 46849983 intron variant A/G snv 0.11
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1885884
rs1885884 		13 46856141 non coding transcript exon variant C/A;G;T snv
CUI: C0013146
Disease: Drug abuse
Drug abuse 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs1885884
rs1885884 		13 46856141 non coding transcript exon variant C/A;G;T snv
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs1923884
rs1923884 		1.000 0.120 13 46847701 intron variant C/T snv 0.12
CUI: C0015674
Disease: Chronic Fatigue Syndrome
Chronic Fatigue Syndrome 		Infections; Musculoskeletal Diseases; Nervous System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1923884
rs1923884 		1.000 0.120 13 46847701 intron variant C/T snv 0.12
CUI: C0235162
Disease: Difficulty sleeping
Difficulty sleeping 		Mental Disorders 0.010 1.000 1 2016 2016
dbSNP: rs1923885
rs1923885 		1.000 0.040 13 46848951 intron variant T/C snv 0.43
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs1923886
rs1923886 		13 46849156 intron variant C/T snv 0.64
CUI: C0239377
Disease: Arm Pain
Arm Pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2019 2019
dbSNP: rs1928040
rs1928040 		1.000 0.040 13 46873101 intron variant G/A snv 0.49
CUI: C0024517
Disease: Major depression, single episode
Major depression, single episode 		Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs2070040
rs2070040 		13 46893491 intron variant G/A snv 0.37
CUI: C0235162
Disease: Difficulty sleeping
Difficulty sleeping 		Mental Disorders 0.010 1.000 1 2016 2016