IL6, interleukin 6, 3569

N. diseases: 2367; N. variants: 22
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 1.000 2 2013 2016
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 1.000 2 2013 2016
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		Skin and Connective Tissue Diseases; Cardiovascular Diseases 0.720 1.000 2 2015 2019
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0023980
Disease: Longevity
Longevity 		0.700 1.000 2 2016 2019
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 1.000 2 2013 2016
dbSNP: rs747126003
rs747126003 		0.689 0.400 7 22728790 missense variant A/G;T snv 4.0E-06
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.020 0.500 2 2009 2012
dbSNP: rs13306435
rs13306435 		1.000 0.080 7 22731420 missense variant T/A;C snv 2.9E-02; 4.2E-06
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2011 2011
dbSNP: rs1554606
rs1554606 		0.925 0.120 7 22729088 intron variant T/A;G snv
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		Nutritional and Metabolic Diseases; Musculoskeletal Diseases 0.010 < 0.001 1 2019 2019
dbSNP: rs1554606
rs1554606 		0.925 0.120 7 22729088 intron variant T/A;G snv
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2069827
rs2069827 		1.000 0.040 7 22725837 non coding transcript exon variant G/C;T snv
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		Skin and Connective Tissue Diseases 0.010 1.000 1 2012 2012
dbSNP: rs2069832
rs2069832 		0.851 0.200 7 22727814 intron variant A/G;T snv
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2008 2008
dbSNP: rs2069832
rs2069832 		0.851 0.200 7 22727814 intron variant A/G;T snv
CUI: C0242966
Disease: Systemic Inflammatory Response Syndrome
Systemic Inflammatory Response Syndrome 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2012 2012
dbSNP: rs2069832
rs2069832 		0.851 0.200 7 22727814 intron variant A/G;T snv
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2008 2008
dbSNP: rs2069832
rs2069832 		0.851 0.200 7 22727814 intron variant A/G;T snv
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.010 1.000 1 2015 2015
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy 		Nervous System Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases 0.010 < 0.001 1 2019 2019
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		Cardiovascular Diseases 0.010 1.000 1 2012 2012
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0426970
Disease: Spastic Quadriplegia
Spastic Quadriplegia 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0041327
Disease: Tuberculosis, Pulmonary
Tuberculosis, Pulmonary 		Infections; Respiratory Tract Diseases 0.010 1.000 1 2018 2018
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C0266929
Disease: Chronic Periodontitis
Chronic Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2017 2017
dbSNP: rs2069837
rs2069837 		0.724 0.520 7 22728408 intron variant A/C;G snv
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2016 2016