KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.020 1.000 2 2014 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0279671
Disease: Cervical Squamous Cell Carcinoma
Cervical Squamous Cell Carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2014 2014
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0751075
Disease: Cancer of Digestive System
Cancer of Digestive System 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C2931822
Disease: Nasopharyngeal carcinoma
Nasopharyngeal carcinoma 		Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases 0.010 1.000 1 2014 2014
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs712
rs712 		0.677 0.360 12 25209618 3 prime UTR variant A/C snv 0.46
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C3146257
Disease: Stage II Colon Cancer AJCC v7
Stage II Colon Cancer AJCC v7 		0.010 1.000 1 2018 2018
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C0278479
Disease: Stage II Colon Cancer
Stage II Colon Cancer 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C4525119
Disease: Stage II Colon Cancer AJCC v8
Stage II Colon Cancer AJCC v8 		0.010 1.000 1 2018 2018