LOX, lysyl oxidase, 4015

N. diseases: 328; N. variants: 14
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.020 1.000 2 2011 2014
dbSNP: rs10519694
rs10519694 		1.000 0.040 5 122071524 intron variant C/T snv 0.21
CUI: C0022578
Disease: Keratoconus
Keratoconus 		Eye Diseases 0.010 1.000 1 2015 2015
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		Nervous System Diseases; Cardiovascular Diseases 0.010 1.000 1 2012 2012
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0242852
Disease: Proliferative vitreoretinopathy
Proliferative vitreoretinopathy 		Eye Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 1.000 1 2015 2015
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2012 2012
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0029172
Disease: Oral Submucous Fibrosis
Oral Submucous Fibrosis 		Stomatognathic Diseases 0.010 1.000 1 2009 2009
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0271055
Disease: Rhegmatogenous retinal detachment
Rhegmatogenous retinal detachment 		Eye Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2011 2011
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2011 2011
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C1456868
Disease: Diabetic foot ulcer
Diabetic foot ulcer 		Skin and Connective Tissue Diseases; Endocrine System Diseases; Cardiovascular Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2011 2011
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800449
rs1800449 		0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2016 2016