ZFHX3, zinc finger homeobox 3, 463

N. diseases: 85; N. variants: 39
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs12932445
rs12932445 		0.925 0.080 16 73035989 intron variant T/C snv 0.18
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1381855646
rs1381855646 		0.925 0.080 16 72959537 synonymous variant G/A snv
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs1381855646
rs1381855646 		0.925 0.080 16 72959537 synonymous variant G/A snv
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs16971436
rs16971436 		0.851 0.080 16 72958864 missense variant T/C;G snv 1.2E-05; 7.1E-02
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs16971436
rs16971436 		0.851 0.080 16 72958864 missense variant T/C;G snv 1.2E-05; 7.1E-02
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs16971436
rs16971436 		0.851 0.080 16 72958864 missense variant T/C;G snv 1.2E-05; 7.1E-02
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs16971436
rs16971436 		0.851 0.080 16 72958864 missense variant T/C;G snv 1.2E-05; 7.1E-02
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2016 2016
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2016 2016
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0206698
Disease: Cholangiocarcinoma
Cholangiocarcinoma 		Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases 0.010 1.000 1 2017 2017
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		Cardiovascular Diseases 0.010 1.000 1 2011 2011
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0235480
Disease: Paroxysmal atrial fibrillation
Paroxysmal atrial fibrillation 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.010 1.000 1 2018 2018
dbSNP: rs2106261
rs2106261 		0.763 0.160 16 73017721 intron variant C/G;T snv
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2011 2011
dbSNP: rs6499600
rs6499600 		1.000 0.080 16 72945475 intron variant C/T snv 0.51
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs879324
rs879324 		1.000 0.080 16 73034779 intron variant G/A snv 0.17
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		Nervous System Diseases; Cardiovascular Diseases 0.010 < 0.001 1 2020 2020
dbSNP: rs756717
rs756717 		16 72962263 intron variant G/A;C snv
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 3 2017 2019
dbSNP: rs1858800
rs1858800 		1.000 0.120 16 72990377 intron variant C/T snv 0.28
CUI: C0017654
Disease: Glomerular Filtration Rate
Glomerular Filtration Rate 		0.700 1.000 2 2019 2019
dbSNP: rs2359171
rs2359171 		1.000 0.080 16 73019123 intron variant T/A snv 0.21
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.700 1.000 2 2018 2018
dbSNP: rs117934006
rs117934006 		16 73392991 intron variant C/T snv 9.6E-02
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs12325540
rs12325540 		16 73346464 intron variant C/T snv 0.18
CUI: C0043094
Disease: Weight Gain
Weight Gain 		Pathological Conditions, Signs and Symptoms 0.700 1.000 1 2019 2019
dbSNP: rs12922127
rs12922127 		16 72925068 intron variant C/T snv 0.13
CUI: C0042834
Disease: Vital capacity
Vital capacity 		0.700 1.000 1 2019 2019