NPY, neuropeptide Y, 4852

N. diseases: 381; N. variants: 12
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 1.000 11 2000 2017
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.050 1.000 5 2006 2015
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.050 1.000 5 2002 2013
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.050 1.000 5 2002 2013
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.040 1.000 4 2001 2012
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.040 1.000 4 2001 2012
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.040 1.000 4 2001 2008
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.040 1.000 4 2002 2013
dbSNP: rs16147
rs16147 		0.695 0.400 7 24283791 upstream gene variant T/C snv 0.48
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.040 1.000 4 2012 2015
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases 0.030 1.000 3 2004 2007
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		Cardiovascular Diseases 0.030 1.000 3 2004 2008
dbSNP: rs1468271
rs1468271 		1.000 0.040 7 24287362 intron variant C/T snv 0.97
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		Nutritional and Metabolic Diseases 0.020 1.000 2 2008 2009
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.020 1.000 2 2006 2007
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.020 1.000 2 2009 2013
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases 0.020 1.000 2 2004 2006
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.020 1.000 2 2009 2013
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.020 1.000 2 2009 2013
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		Eye Diseases 0.020 1.000 2 2000 2006
dbSNP: rs16139
rs16139 		0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.020 1.000 2 2011 2013
dbSNP: rs16147
rs16147 		0.695 0.400 7 24283791 upstream gene variant T/C snv 0.48
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.020 1.000 2 2015 2016
dbSNP: rs16147
rs16147 		0.695 0.400 7 24283791 upstream gene variant T/C snv 0.48
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.020 0.500 2 2014 2015
dbSNP: rs17149106
rs17149106 		0.925 0.160 7 24283588 upstream gene variant G/T snv
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.020 1.000 2 2011 2016
dbSNP: rs1356639869
rs1356639869 		1.000 0.040 7 24289527 missense variant C/A snv
CUI: C0013473
Disease: Eating Disorders
Eating Disorders 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs1356639869
rs1356639869 		1.000 0.040 7 24289527 missense variant C/A snv
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		Mental Disorders 0.010 1.000 1 2007 2007
dbSNP: rs1468271
rs1468271 		1.000 0.040 7 24287362 intron variant C/T snv 0.97
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008