NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0280141
Disease: Acute Undifferentiated Leukemia
Acute Undifferentiated Leukemia 		0.010 1.000 1 2014 2014
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		Neoplasms 0.700 1.000 1 2016 2016
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		Neoplasms 0.700 1.000 1 2016 2016
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0334279
Disease: Adenocarcinoma, intestinal type
Adenocarcinoma, intestinal type 		Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0206686
Disease: Adrenocortical carcinoma
Adrenocortical carcinoma 		Neoplasms; Endocrine System Diseases 0.700 1.000 1 2016 2016
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C0206686
Disease: Adrenocortical carcinoma
Adrenocortical carcinoma 		Neoplasms; Endocrine System Diseases 0.700 1.000 1 2016 2016
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 1997 1997
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 1997 1997
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 1997 1997
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 1997 1997
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 1997 1997
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2012 2012
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2012 2012
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2011 2011
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0280781
Disease: Adult Pilocytic Astrocytoma
Adult Pilocytic Astrocytoma 		Neoplasms 0.010 1.000 1 2007 2007
dbSNP: rs8453
rs8453 		1.000 0.040 1 114716978 3 prime UTR variant G/T snv 0.11
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		Mental Disorders 0.800 1.000 1 2014 2014
dbSNP: rs121434596
rs121434596 		0.677 0.440 1 114716123 missense variant C/A;G;T snv 4.0E-06; 4.0E-06
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases 0.020 0.500 2 2007 2015
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997