NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 32 1989 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 30 1989 2019
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.780 1.000 21 1989 2016
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 16 2005 2019
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.700 1.000 13 1989 2014
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.100 1.000 12 2011 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.100 1.000 11 2011 2019
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.720 1.000 10 1989 2016
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.090 1.000 9 2011 2019
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.700 1.000 9 1984 2014
dbSNP: rs121434595
rs121434595 		0.708 0.320 1 114716124 missense variant C/A;G;T snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.700 1.000 9 1989 2014
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		Digestive System Diseases; Neoplasms 0.700 1.000 9 2006 2016
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		Digestive System Diseases; Neoplasms 0.700 1.000 8 2006 2016
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		Neoplasms 0.710 1.000 7 1987 2016
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		Neoplasms 0.700 1.000 7 1987 2016
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0349639
Disease: Juvenile Myelomonocytic Leukemia
Juvenile Myelomonocytic Leukemia 		Neoplasms; Hemic and Lymphatic Diseases 0.710 1.000 6 2000 2012
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases 0.700 1.000 5 2000 2010
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.700 1.000 4 2002 2013
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.040 1.000 4 2011 2018
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma 		Neoplasms 0.030 1.000 3 2015 2016
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma 		Neoplasms 0.030 1.000 3 2015 2016
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		Neoplasms; Endocrine System Diseases 0.720 1.000 3 2016 2017
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma 		Neoplasms 0.030 1.000 3 2015 2016
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2013 2017
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.030 1.000 3 2015 2017