TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs11196218
rs11196218 		0.925 0.160 10 113080735 intron variant G/A snv 0.25
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.020 < 0.001 2 2010 2012
dbSNP: rs11196172
rs11196172 		0.708 0.200 10 112967084 intron variant G/A snv 0.13
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs11196172
rs11196172 		0.708 0.200 10 112967084 intron variant G/A snv 0.13
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs1427214163
rs1427214163 		1.000 0.080 10 113151879 missense variant C/T snv 7.0E-06
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.010 < 0.001 1 2007 2007
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		Neoplasms; Nervous System Diseases 0.010 < 0.001 1 2002 2002
dbSNP: rs77961654
rs77961654 		1.000 0.080 10 113165610 missense variant C/A snv 5.3E-02 2.9E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease 		Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 < 0.001 1 2014 2014
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0041349
Disease: Nephritis, Tubulointerstitial
Nephritis, Tubulointerstitial 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 < 0.001 1 2014 2014
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0027707
Disease: Nephritis, Interstitial
Nephritis, Interstitial 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 < 0.001 1 2014 2014
dbSNP: rs11196236
rs11196236 		0.925 0.160 10 113127963 intron variant T/C snv 0.16
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.030 0.333 3 2009 2013
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.090 0.444 9 2007 2017
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.040 0.500 4 2007 2013
dbSNP: rs290487
rs290487 		0.776 0.280 10 113149972 intron variant C/T snv 0.16
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.020 0.500 2 2010 2012
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.020 0.500 2 2008 2014
dbSNP: rs290487
rs290487 		0.776 0.280 10 113149972 intron variant C/T snv 0.16
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 0.667 15 2007 2015
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.030 0.667 3 2009 2018
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		Cardiovascular Diseases 0.030 0.667 3 2008 2010
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.030 0.667 3 2008 2010
dbSNP: rs11196218
rs11196218 		0.925 0.160 10 113080735 intron variant G/A snv 0.25
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 0.700 10 2007 2015
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.040 0.750 4 2007 2019
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		Nutritional and Metabolic Diseases 0.040 0.750 4 2006 2017
dbSNP: rs11196172
rs11196172 		0.708 0.200 10 112967084 intron variant G/A snv 0.13
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.820 0.833 6 2014 2019
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		Cardiovascular Diseases 0.060 0.833 6 2008 2017