TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1232013698
rs1232013698 		6 31577208 missense variant G/T snv 4.1E-06
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2009 2009
dbSNP: rs1250554906
rs1250554906 		1.000 0.120 6 31576808 missense variant G/A snv 4.1E-06 7.0E-06
CUI: C0393814
Disease: Hereditary liability to pressure palsies
Hereditary liability to pressure palsies 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1250915035
rs1250915035 		0.925 6 31576537 missense variant C/T snv 4.0E-06
CUI: C0374997
Disease: Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 		0.010 1.000 1 2017 2017
dbSNP: rs1250915035
rs1250915035 		0.925 6 31576537 missense variant C/T snv 4.0E-06
CUI: C3826128
Disease: Infection in children
Infection in children 		0.010 1.000 1 2017 2017
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1363819544
rs1363819544 		1.000 0.160 6 31577126 synonymous variant A/G snv 7.0E-06
CUI: C0522624
Disease: Subcutaneous panniculitis-like T-cell lymphoma
Subcutaneous panniculitis-like T-cell lymphoma 		Neoplasms; Skin and Connective Tissue Diseases; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2018 2018
dbSNP: rs1400328611
rs1400328611 		1.000 0.080 6 31575804 frameshift variant AG/- del
CUI: C0281899
Disease: Prolapsed lumbar disc
Prolapsed lumbar disc 		Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases 0.010 1.000 1 2011 2011
dbSNP: rs1411364031
rs1411364031 		0.882 0.040 6 31577502 missense variant T/C snv 7.0E-06
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1411364031
rs1411364031 		0.882 0.040 6 31577502 missense variant T/C snv 7.0E-06
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1411364031
rs1411364031 		0.882 0.040 6 31577502 missense variant T/C snv 7.0E-06
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1418646618
rs1418646618 		1.000 0.080 6 31575843 missense variant C/G snv 1.2E-05 7.0E-06
CUI: C0024534
Disease: Malaria, Cerebral
Malaria, Cerebral 		Infections; Nervous System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1454071630
rs1454071630 		1.000 0.040 6 31577259 missense variant G/A;T snv 8.1E-06
CUI: C0343055
Disease: Generalized pustular psoriasis
Generalized pustular psoriasis 		Skin and Connective Tissue Diseases 0.010 1.000 1 2012 2012
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2015 2015
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		Nervous System Diseases; Cardiovascular Diseases 0.010 1.000 1 2011 2011
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0036202
Disease: Sarcoidosis
Sarcoidosis 		Hemic and Lymphatic Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0392077
Disease: Cardiac sarcoidosis
Cardiac sarcoidosis 		Hemic and Lymphatic Diseases; Cardiovascular Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		Digestive System Diseases 0.010 1.000 1 2015 2015
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2016 2016