TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1232013698
rs1232013698 		6 31577208 missense variant G/T snv 4.1E-06
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2009 2009
dbSNP: rs3093664
rs3093664 		6 31576865 intron variant A/G snv 6.9E-02 7.7E-02
CUI: C0043144
Disease: Wheezing
Wheezing 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2016 2016
dbSNP: rs3093664
rs3093664 		6 31576865 intron variant A/G snv 6.9E-02 7.7E-02
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		0.700 1.000 1 2018 2018
dbSNP: rs281865419
rs281865419 		6 31577157 missense variant C/T snv 8.1E-06 7.0E-06
CUI: C4016415
Disease: TNF RECEPTOR BINDING, ALTERED
TNF RECEPTOR BINDING, ALTERED 		0.700 0
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.070 0.857 7 2011 2019
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.060 1.000 6 2007 2015
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0036690
Disease: Septicemia
Septicemia 		Pathological Conditions, Signs and Symptoms; Infections 0.050 1.000 5 2008 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.050 0.800 5 2012 2018
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.050 0.800 5 2012 2018
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.050 0.800 5 2012 2018
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		Respiratory Tract Diseases 0.040 1.000 4 2010 2019
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0243026
Disease: Sepsis
Sepsis 		Pathological Conditions, Signs and Symptoms; Infections 0.040 1.000 4 2012 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.040 0.500 4 2006 2019
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.040 0.750 4 2013 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		Digestive System Diseases; Neoplasms 0.040 1.000 4 2013 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 0.750 4 2013 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		Digestive System Diseases; Neoplasms 0.040 1.000 4 2013 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		Musculoskeletal Diseases 0.030 1.000 3 2013 2018
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.030 1.000 3 2010 2018
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0041327
Disease: Tuberculosis, Pulmonary
Tuberculosis, Pulmonary 		Infections; Respiratory Tract Diseases 0.030 0.667 3 2011 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.030 0.667 3 2017 2019
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		Skin and Connective Tissue Diseases; Immune System Diseases 0.030 0.667 3 2018 2019
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.030 1.000 3 2012 2014
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		Digestive System Diseases 0.030 1.000 3 2016 2017
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0023343
Disease: Leprosy
Leprosy 		Infections 0.030 1.000 3 2015 2017