XRCC3, X-ray repair cross complementing 3, 7517

N. diseases: 184; N. variants: 24
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1178552124
rs1178552124 		1.000 0.040 14 103703253 synonymous variant G/A snv
CUI: C0029172
Disease: Oral Submucous Fibrosis
Oral Submucous Fibrosis 		Stomatognathic Diseases 0.010 1.000 1 2012 2012
dbSNP: rs3212079
rs3212079 		1.000 0.080 14 103704128 3 prime UTR variant G/A snv 5.2E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs3212112
rs3212112 		1.000 0.040 14 103699345 intron variant A/C snv 7.1E-03 2.2E-02
CUI: C0017638
Disease: Glioma
Glioma 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs861537
rs861537 		1.000 0.080 14 103700738 intron variant C/T snv 0.61 0.61
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1360602468
rs1360602468 		0.925 0.080 14 103698904 missense variant G/C;T snv
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		Neoplasms 0.010 1.000 1 2011 2011
dbSNP: rs1360602468
rs1360602468 		0.925 0.080 14 103698904 missense variant G/C;T snv
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs3212057
rs3212057 		0.925 0.080 14 103707128 missense variant C/T snv 1.4E-03 6.3E-03
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs3212057
rs3212057 		0.925 0.080 14 103707128 missense variant C/T snv 1.4E-03 6.3E-03
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs45603942
rs45603942 		0.925 0.080 14 103712895 5 prime UTR variant G/A snv 1.2E-04
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs45603942
rs45603942 		0.925 0.080 14 103712895 5 prime UTR variant G/A snv 1.2E-04
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs861528
rs861528 		0.925 0.080 14 103716661 intron variant C/T snv 0.17
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs861528
rs861528 		0.925 0.080 14 103716661 intron variant C/T snv 0.17
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs861529
rs861529 		0.925 0.080 14 103712977 3 prime UTR variant T/C snv 0.91
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2007 2007
dbSNP: rs861529
rs861529 		0.925 0.080 14 103712977 3 prime UTR variant T/C snv 0.91
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2007 2007
dbSNP: rs709399
rs709399 		0.882 0.080 14 103701208 3 prime UTR variant G/A snv 0.59 0.61
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs709399
rs709399 		0.882 0.080 14 103701208 3 prime UTR variant G/A snv 0.59 0.61
CUI: C0007115
Disease: Malignant neoplasm of thyroid
Malignant neoplasm of thyroid 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs709399
rs709399 		0.882 0.080 14 103701208 3 prime UTR variant G/A snv 0.59 0.61
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs77381814
rs77381814 		0.882 0.080 14 103699410 missense variant C/T snv 1.5E-03 5.9E-03
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2013 2013
dbSNP: rs77381814
rs77381814 		0.882 0.080 14 103699410 missense variant C/T snv 1.5E-03 5.9E-03
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2013 2013
dbSNP: rs77381814
rs77381814 		0.882 0.080 14 103699410 missense variant C/T snv 1.5E-03 5.9E-03
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2013 2013
dbSNP: rs861531
rs861531 		0.882 0.120 14 103706470 3 prime UTR variant C/A snv 0.32
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs861531
rs861531 		0.882 0.120 14 103706470 3 prime UTR variant C/A snv 0.32
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs861531
rs861531 		0.882 0.120 14 103706470 3 prime UTR variant C/A snv 0.32
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs28903081
rs28903081 		0.851 0.200 14 103698934 missense variant C/A;T snv 4.5E-06; 4.3E-04
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.010 1.000 1 2018 2018
dbSNP: rs28903081
rs28903081 		0.851 0.200 14 103698934 missense variant C/A;T snv 4.5E-06; 4.3E-04
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 < 0.001 1 2016 2016