PDCD6, programmed cell death 6, 10016

N. diseases: 45; N. variants: 3
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3756712
rs3756712
Entrez Id: 10016;57491
Gene Symbol: PDCD6;AHRR
PDCD6;AHRR
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Overall, our results indicate that PDCD6 rs3756712 T>G polymorphism was significantly associated with decreased risk of cancer under codominant (OR = 0.82, 95%CI = 0.70-0.96, <i>p</i> = 0.01, TG vs TT; OR = 0.53, 95%CI = 0.39-0.72, <i>p</i> < 0.0001, GG vs TT), dominant (OR = 0.76, 95%CI = 0.66-0.89, <i>p</i> = 0.0004, TG+GG vs TT), recessive (OR = 0.57, 95%CI = 0.43-0.78, <i>p</i> = 0.0003, GG vs TT+TG), and allele (OR = 0.76, 95%CI = 0.67-0.86, <i>p</i> < 0.00001, G vs T) genetic model. 29872511 2018