CDK4, cyclin dependent kinase 4, 1019

N. diseases: 433; N. variants: 8
Disease: Testicular Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11547328
rs11547328
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
CUI: C0039590
Disease:
Testicular Neoplasms 		0.010 GeneticVariation BEFREE However, 'knock-in' mice homozygous for the CDK4(R24C) mutation were noted to develop multiple neoplasia, most commonly including endocrine tumours: pituitary adenomas, insulinomas and Leydig cell testicular tumours. 12904177 2003