ADAM10, ADAM metallopeptidase domain 10, 102

N. diseases: 224; N. variants: 27
Disease: Severe Sepsis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs653765
rs653765
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
CUI: C1719672
Disease:
Severe Sepsis 		0.010 GeneticVariation BEFREE Our data initially indicated the ADAM10 rs653765 polymorphism was associated with the development of severe sepsis; the risk CC genotype could functionally affect the expression level of ADAM10 mRNA and was accompanied by the up-regulation of its substrates. 25888255 2015