CDK6, cyclin dependent kinase 6, 1021

N. diseases: 266; N. variants: 27
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs606231255
rs606231255
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C4015156
Disease:
MICROCEPHALY 12, PRIMARY, AUTOSOMAL RECESSIVE 		T 0.800 CausalMutation CLINVAR
dbSNP: rs606231255
rs606231255
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C4015156
Disease:
MICROCEPHALY 12, PRIMARY, AUTOSOMAL RECESSIVE 		0.800 GeneticVariation UNIPROT
dbSNP: rs2040494
rs2040494
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0489786
Disease:
Height 		0.700 GeneticVariation GWASDB A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. 19570815 2009
dbSNP: rs759338099
rs759338099
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		0.010 GeneticVariation BEFREE After our recent report that a deregulation of Cdk5 activity by p25 may contribute to pathogenesis of amyotrophic lateral sclerosis (ALS), we further examined the possible involvement of other Cdks in mice expressing a mutant form of superoxide dismutase (SOD1(G37R)) linked to ALS. 12657672 2003
dbSNP: rs56201652
rs56201652
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0004238
Disease:
Atrial Fibrillation 		G 0.700 GeneticVariation GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
dbSNP: rs8179
rs8179
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C4048328
Disease:
cervical cancer 		0.010 GeneticVariation BEFREE CDK6 rs8179 and rs42033 were correlated to the decreased risk of cervical cancer in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019
dbSNP: rs8179
rs8179
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0302592
Disease:
Cervix carcinoma 		0.010 GeneticVariation BEFREE CDK6 rs8179 and rs42033 were correlated to the decreased risk of cervical cancer in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019
dbSNP: rs8179
rs8179
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0007847
Disease:
Malignant tumor of cervix 		0.010 GeneticVariation BEFREE CDK6 rs8179 and rs42033 were correlated to the decreased risk of cervical cancer in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019
dbSNP: rs42033
rs42033
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C4048328
Disease:
cervical cancer 		0.010 GeneticVariation BEFREE CDK6 rs8179 and rs42033</span> were correlated to the decreased risk of cervical cancer</span> in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019
dbSNP: rs42033
rs42033
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0302592
Disease:
Cervix carcinoma 		0.010 GeneticVariation BEFREE CDK6 rs8179 and rs42033</span> were correlated to the decreased risk of cervical cancer</span> in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019
dbSNP: rs42033
rs42033
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0007847
Disease:
Malignant tumor of cervix 		0.010 GeneticVariation BEFREE CDK6 rs8179 and rs42033</span> were correlated to the decreased risk of cervical cancer</span> in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019
dbSNP: rs42377
rs42377
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs42039
rs42039
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0005890
Disease:
Body Height 		T 0.700 GeneticVariation GWASCAT Defining the role of common variation in the genomic and biological architecture of adult human height. 25282103 2014
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.800 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0200638
Disease:
Eosinophil count procedure 		0.800 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs2040494
rs2040494
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0750880
Disease:
Monocyte count result 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0200637
Disease:
Monocyte count procedure 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0200633
Disease:
Neutrophil count (procedure) 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs73406759
rs73406759
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs4272
rs4272
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0003873
Disease:
Rheumatoid Arthritis 		A 0.800 GeneticVariation GWASCAT Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. 30423114 2019
dbSNP: rs445
rs445
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C1445957
Disease:
Serum total cholesterol measurement 		T 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs4272
rs4272
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0003873
Disease:
Rheumatoid Arthritis 		G 0.800 GeneticVariation GWASCAT Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342 2014