CDK6, cyclin dependent kinase 6, 1021

N. diseases: 266; N. variants: 27
Disease: Rheumatoid Arthritis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs42041
rs42041
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.020 GeneticVariation BEFREE However, there was no evidence for association of rs42041 (CDK6) and rs6682654 (CD244) with RA susceptibility in this UK population. 19435719 2010
dbSNP: rs42041
rs42041
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.020 GeneticVariation BEFREE The TT and CC/CG genotypes of 2 single-nucleotide polymorphisms, rs4810485 (CD40) and rs42041 (CDK6), respectively, were associated with a higher rate of joint destruction in ACPA-positive RA patients (P=0.003 and P=0.012, respectively), with rs4810485 being significant after Bonferroni correction for multiple testing. 19644859 2009