CDKN1A, cyclin dependent kinase inhibitor 1A, 1026

N. diseases: 490; N. variants: 17
Disease: Primary malignant neoplasm of lung ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE In summary, based on our meta-analysis, p21 Ser31Arg polymorphism does not appear to act as an independent lung cancer risk factor and is more likely to act together with other genetic and non-genetic factors in the development of lung cancer; this needs further investigation. 22009857 2011
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.020 GeneticVariation BEFREE We therefore investigated the combined effects of polymorphisms in TP53 (Arg72Pro) and p21/CDKN1A (Ser31Arg) and smoking on lung cancer risk. 17059853 2007