SPON1, spondin 1, 10418

N. diseases: 31; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11023139
rs11023139
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0002395
Disease:
Alzheimer's Disease
0.800 GeneticVariation GWASDB Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. 23535033 2014
dbSNP: rs11023139
rs11023139
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0002395
Disease:
Alzheimer's Disease
0.800 GeneticVariation GWASCAT Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. 23535033 2014
dbSNP: rs1969539
rs1969539
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7102710
rs7102710
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0005890
Disease:
Body Height
C 0.700 GeneticVariation GWASCAT Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies. 31564439 2019
dbSNP: rs10832169
rs10832169
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C2985280
Disease:
Blood Protein Measurement
A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs11023056
rs11023056
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C2985280
Disease:
Blood Protein Measurement
G 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs2618521
rs2618521
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C2985280
Disease:
Blood Protein Measurement
G 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs117865811
rs117865811
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0523979
Disease:
Vitamin D3 measurement
G 0.700 GeneticVariation GWASCAT Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. 28757204 2017
dbSNP: rs117865811
rs117865811
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0919758
Disease:
Vitamin D measurement
G 0.700 GeneticVariation GWASCAT Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. 28757204 2017
dbSNP: rs2303975
rs2303975
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0392885
Disease:
High density lipoprotein measurement
A 0.700 GeneticVariation GWASCAT Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. 28334899 2017
dbSNP: rs7102710
rs7102710
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0017741
Disease:
Glucose tolerance test
C 0.700 GeneticVariation GWASCAT Genetic determinants of circulating GIP and GLP-1 concentrations. 29093273 2017
dbSNP: rs7102710
rs7102710
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0337437
Disease:
Glucagon measurement
C 0.700 GeneticVariation GWASCAT Genetic determinants of circulating GIP and GLP-1 concentrations. 29093273 2017
dbSNP: rs17556665
rs17556665
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0201657
Disease:
C-reactive protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. 22228203 2012
dbSNP: rs2618516
rs2618516
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0002395
Disease:
Alzheimer's Disease
0.010 GeneticVariation BEFREE The rs2618516 in the spondin 1 gene (SPON1) has been associated with AD risk and brain structure in the elderly. 29573041 2018
dbSNP: rs2618516
rs2618516
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0497327
Disease:
Dementia
0.010 GeneticVariation BEFREE The association of connectivity with the SPON1 variant at rs2618516 on chromosome 11 (11p15.2) reached connectome-wide, genome-wide significance after stringent statistical corrections were enforced, and it was replicated in an independent subsample. rs2618516 was shown to affect brain structure in an elderly population with varying degrees of dementia. 23471985 2013
dbSNP: rs2618516
rs2618516
Entrez Id: 10418
Gene Symbol: SPON1
SPON1
CUI: C0011265
Disease:
Presenile dementia
0.010 GeneticVariation BEFREE The association of connectivity with the SPON1 variant at rs2618516 on chromosome 11 (11p15.2) reached connectome-wide, genome-wide significance after stringent statistical corrections were enforced, and it was replicated in an independent subsample. rs2618516 was shown to affect brain structure in an elderly population with varying degrees of dementia. 23471985 2013