PDLIM5, PDZ and LIM domain 5, 10611

N. diseases: 148; N. variants: 19
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12500426
rs12500426
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C2931822
Disease:
Nasopharyngeal carcinoma 		0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C2931822
Disease:
Nasopharyngeal carcinoma 		0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
dbSNP: rs1329032366
rs1329032366
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE A murine in vivo xenograft model of A127T paxillin showed an increase in tumor growth, cell proliferation, and invasion. 18172305 2008
dbSNP: rs1329032366
rs1329032366
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C1269955
Disease:
Tumor Cell Invasion 		0.010 GeneticVariation BEFREE A murine in vivo xenograft model of A127T paxillin showed an increase in tumor growth, cell proliferation, and invasion. 18172305 2008
dbSNP: rs1318234609
rs1318234609
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0242343
Disease:
Panhypopituitarism 		0.010 GeneticVariation BEFREE A novel mutation (V101A) of the LHX4 gene in a Japanese patient with combined pituitary hormone deficiency. 19856252 2010
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0600139
Disease:
Prostate carcinoma 		C 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016 2018
dbSNP: rs200495769
rs200495769
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C1961102
Disease:
Precursor Cell Lymphoblastic Leukemia Lymphoma 		T 0.700 GeneticVariation GWASCAT Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia. 27114598 2016
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Four SNPs were associated with aggressive PrCa, while three other SNPs showed potential interactions for PrCa by family history of PrCa (rs8102476; 19q13), lung cancer (rs17021918; 4q22), and breast cancer (rs10896449; 11q13). 23573233 2013
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE Four SNPs were associated with aggressive PrCa, while three other SNPs showed potential interactions for PrCa by family history of PrCa (rs8102476; 19q13), lung cancer (rs17021918; 4q22), and breast cancer (rs10896449; 11q13). 23573233 2013
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0684249
Disease:
Carcinoma of lung 		0.010 GeneticVariation BEFREE Four SNPs were associated with aggressive PrCa, while three other SNPs showed potential interactions for PrCa by family history of PrCa (rs8102476; 19q13), lung cancer (rs17021918; 4q22), and breast cancer (rs10896449; 11q13). 23573233 2013
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Four SNPs were associated with aggressive PrCa, while three other SNPs showed potential interactions for PrCa by family history of PrCa (rs8102476; 19q13), lung cancer (rs17021918; 4q22), and breast cancer (rs10896449; 11q13). 23573233 2013
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Four SNPs were associated with aggressive PrCa, while three other SNPs showed potential interactions for PrCa by family history of PrCa (rs8102476; 19q13), lung cancer (rs17021918; 4q22), and breast cancer (rs10896449; 11q13). 23573233 2013
dbSNP: rs4699299
rs4699299
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0042133
Disease:
Uterine Fibroids 		T 0.700 GeneticVariation GWASCAT Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. 31649266 2019
dbSNP: rs4699299
rs4699299
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C2242776
Disease:
Plexiform leiomyoma 		T 0.700 GeneticVariation GWASCAT Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. 31649266 2019
dbSNP: rs11097431
rs11097431
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0005586
Disease:
Bipolar Disorder 		0.010 GeneticVariation BEFREE However, no association was detected between the rs11097431 polymorphism either with bipolar disorder or with schizophrenia. 24064681 2013
dbSNP: rs11097431
rs11097431
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE However, no association was detected between the rs11097431 polymorphism either with bipolar disorder or with schizophrenia. 24064681 2013
dbSNP: rs2452600
rs2452600
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C1956346
Disease:
Coronary Artery Disease 		T 0.700 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
dbSNP: rs12500426
rs12500426
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		A 0.700 GeneticVariation GWASDB Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 19767753 2009
dbSNP: rs12500426
rs12500426
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0600139
Disease:
Prostate carcinoma 		0.700 GeneticVariation GWASCAT Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 19767753 2009
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0600139
Disease:
Prostate carcinoma 		0.700 GeneticVariation GWASCAT Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 19767753 2009
dbSNP: rs17021918
rs17021918
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		T 0.700 GeneticVariation GWASDB Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 19767753 2009
dbSNP: rs2433322
rs2433322
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0036341
Disease:
Schizophrenia 		0.020 GeneticVariation BEFREE In addition, high linkage disequilibrium was observed between rs2433320 and rs2433322 (D'=0.880), and haplotypes constructed from the two SNPs were significantly associated with schizophrenia (global P=0.00019, even after strict Bonferroni correction). 18021463 2008
dbSNP: rs200298588
rs200298588
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		0.010 GeneticVariation BEFREE Limd1(-/-) mice are predisposed to chemical-induced lung adenocarcinoma and genetic inactivation of Limd1 in mice heterozygous for oncogenic K-Ras(G12D) markedly increased tumor initiation, promotion, and mortality. 19060205 2008
dbSNP: rs200298588
rs200298588
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C0598935
Disease:
Tumor Initiation 		0.010 GeneticVariation BEFREE Limd1(-/-) mice are predisposed to chemical-induced lung adenocarcinoma and genetic inactivation of Limd1 in mice heterozygous for oncogenic K-Ras(G12D) markedly increased tumor initiation, promotion, and mortality. 19060205 2008
dbSNP: rs767864210
rs767864210
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
CUI: C1623038
Disease:
Cirrhosis 		0.010 GeneticVariation BEFREE Mutated nucleotides of the Enh1/X-promoter, especially G1053A and G1229A mutations in the HBV subgenotype C2 of patients with cirrhosis, can be risk factors for hepatocarcinogenesis, and this might be due to an increase in the HBx levels through the transactivation of the Enh1/X-promoter. 20550526 2010