RAI1, retinoic acid induced 1, 10743

N. diseases: 205; N. variants: 22
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11868035
rs11868035
Entrez Id: 6720;10743
Gene Symbol: SREBF1;RAI1
SREBF1;RAI1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE These findings indicate that the SREBP-1c SNPs rs2297508 and rs11868035 are associated with a significantly increased risk of T2DM and dyslipidemia in the Chinese population. 18692268 2008
dbSNP: rs11868035
rs11868035
Entrez Id: 6720;10743
Gene Symbol: SREBF1;RAI1
SREBF1;RAI1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 GeneticVariation BEFREE The minor alleles of rs2297508, rs11868035, and rs1889018 (linkage disequilibrium R(2) = 0.6-0.8) associated with a modestly increased risk of type 2 diabetes (rs2297508: OR 1.17 [95% CI 1.05-1.30], P = 0.003), which was confirmed in meta-analyses of all published studies (rs2297508 G-allele: 1.08 [1.03-1.14] per allele, P = 0.001). 18192539 2008