FOXN3, forkhead box N3, 1112

N. diseases: 40; N. variants: 13
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4899973
rs4899973
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0033845
Disease:
Pseudotumor Cerebri 		0.700 GeneticVariation GWASCAT Genetic Survey of Adult-Onset Idiopathic Intracranial Hypertension. 29608535 2019
dbSNP: rs4904523
rs4904523
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs55985762
rs55985762
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs4904523
rs4904523
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs55985762
rs55985762
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
dbSNP: rs10484021
rs10484021
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs11626209
rs11626209
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs12147030
rs12147030
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs12431798
rs12431798
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs7147651
rs7147651
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs7147651
rs7147651
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs7153598
rs7153598
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs8009377
rs8009377
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs8004664
rs8004664
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0428568
Disease:
Fasting blood glucose measurement 		A 0.700 GeneticVariation GWASCAT A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. 22581228 2012
dbSNP: rs8020333
rs8020333
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0428568
Disease:
Fasting blood glucose measurement 		0.700 GeneticVariation GWASDB Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. 22885924 2012
dbSNP: rs8020333
rs8020333
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C1261430
Disease:
Fasting blood sugar result 		0.700 GeneticVariation GWASDB Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. 22885924 2012
dbSNP: rs3783853
rs3783853
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0036341
Disease:
Schizophrenia 		0.700 GeneticVariation GWASDB Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
dbSNP: rs8004664
rs8004664
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 GeneticVariation BEFREE 92 participants (49±13 years, body mass index: 32±6 kg/m<sup>2</sup>, 28 with and 64 without type 2 diabetes mellitus) were genotyped at rs8004664. 31543974 2019
dbSNP: rs8004664
rs8004664
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0020456
Disease:
Hyperglycemia 		0.010 GeneticVariation BEFREE Recently, we reported that primary hepatocytes from rs8004664 hyperglycemia risk allele carriers have increased FOXN3 transcript and protein levels and liver-limited overexpression of human FOXN3, a transcriptional repressor that had not been implicated in metabolic regulation previously, increases fasting blood glucose in zebrafish. 29996093 2018