CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10399931
rs10399931
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0004096
Disease:
Asthma
0.030 GeneticVariation BEFREE The rs10399931 CT/TT genotype increased the risk of asthma under the dominant model (<i>P</i> = 0.031, OR = 1.428, 95% CI, 1.033-1.974), while the CT genotype showed the same tendency under the heterozygous model (<i>P</i> = 0.003, OR = 1.680, 95% CI, 1.186-2.380). 30988078 2019
dbSNP: rs10399931
rs10399931
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0004096
Disease:
Asthma
0.030 GeneticVariation BEFREE Our findings suggest that the CHI3L1 polymorphisms rs1538372 and rs10399931 can be used as genetic markers for predicting asthma risk in the Taiwanese population. 25056157 2014
dbSNP: rs10399931
rs10399931
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0004096
Disease:
Asthma
0.030 GeneticVariation BEFREE Interestingly, it has been reported that rs10399931 (-329 G/A) of CHI3LI contributes to the inter-individual plasma YKL-40 levels in patients with sarcoidosis, and that rs4950928 (-131 C/G) is a susceptibility polymorphism for asthma and a decline in lung function. 19421404 2009