CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Disease: Sarcoidosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10399931
rs10399931
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036202
Disease:
Sarcoidosis 		0.020 GeneticVariation BEFREE In the present study, we have examined two functional variants of the promoter region of CHI3L1 gene (CHI3L1-1 (rs4950928) and CHI3L1-2 (rs10399931) that have been reported earlier to be associated with schizophrenia and sarcoidosis. 20300754 2011
dbSNP: rs10399931
rs10399931
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036202
Disease:
Sarcoidosis 		0.020 GeneticVariation BEFREE Interestingly, it has been reported that rs10399931 (-329 G/A) of CHI3LI contributes to the inter-individual plasma YKL-40 levels in patients with sarcoidosis, and that rs4950928 (-131 C/G) is a susceptibility polymorphism for asthma and a decline in lung function. 19421404 2009