CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4950928
rs4950928
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036341
Disease:
Schizophrenia
0.040 GeneticVariation BEFREE We recently reported a significant association between schizophrenia and SNP rs4950928, which is located in the promoter region of the CHI3L1 gene, in a Japanese population. 22366530 2012
dbSNP: rs4950928
rs4950928
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036341
Disease:
Schizophrenia
0.040 GeneticVariation BEFREE In the present study, we have examined two functional variants of the promoter region of CHI3L1 gene (CHI3L1-1 (rs4950928) and CHI3L1-2 (rs10399931) that have been reported earlier to be associated with schizophrenia and sarcoidosis. 20300754 2011
dbSNP: rs4950928
rs4950928
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036341
Disease:
Schizophrenia
0.040 GeneticVariation BEFREE We found significant associations between single nucleotide polymorphism (SNP) 4/rs4950928 (p=0.009), which is located in the promoter region of the CHI3L1 gene, and haplotypes including this SNP and schizophrenia (the most significant global p<0.001). 20051317 2010
dbSNP: rs4950928
rs4950928
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036341
Disease:
Schizophrenia
0.040 GeneticVariation BEFREE Recently, three common polymorphisms in the promoter region of the Chitinase 3-Like 1 (CHI3L1) gene, rs6691378, rs10399805 and rs4950928, have been identified as schizophrenia predisposing single nucleotide polymorphisms (SNPs) in the Han Chinese population. 18767121 2009