KLF12, Kruppel like factor 12, 11278

N. diseases: 58; N. variants: 20
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1887346
rs1887346
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.010 GeneticVariation BEFREE In conclusion, our findings indicate that the KLF12 rs1887346</span> and rs9565072 polymorphisms do not play a relevant role in RA. 21658422 2011
dbSNP: rs9318227
rs9318227
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C1332977
Disease:
Childhood Leukemia 		0.010 GeneticVariation BEFREE The locus of rs974120 shows marks of transcriptional activity in leukemia according to ENCODE data. rs10251201 (7p21.3), rs9318227 (13q22.1), and rs10405859 (19q13.32) were associated with markers related to leukemogenesis and immune and inflammatory responses. 28375557 2017
dbSNP: rs9318227
rs9318227
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0598766
Disease:
Leukemogenesis 		0.010 GeneticVariation BEFREE The locus of rs974120 shows marks of transcriptional activity in leukemia according to ENCODE data. rs10251201 (7p21.3), rs9318227 (13q22.1), and rs10405859 (19q13.32) were associated with markers related to leukemogenesis and immune and inflammatory responses. 28375557 2017
dbSNP: rs9318227
rs9318227
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0023418
Disease:
leukemia 		0.010 GeneticVariation BEFREE The locus of rs974120 shows marks of transcriptional activity in leukemia according to ENCODE data. rs10251201 (7p21.3), rs9318227 (13q22.1), and rs10405859 (19q13.32) were associated with markers related to leukemogenesis and immune and inflammatory responses. 28375557 2017
dbSNP: rs9565072
rs9565072
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.010 GeneticVariation BEFREE In conclusion, our findings indicate that the KLF12 rs1887346 and rs9565072 polymorphisms do not play a relevant role in RA. 21658422 2011
dbSNP: rs12429889
rs12429889
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0085298
Disease:
Sudden Cardiac Death 		0.700 GeneticVariation GWASCAT GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. 21658281 2011
dbSNP: rs12877581
rs12877581
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of schizophrenia in Ashkenazi Jews. 26198764 2015
dbSNP: rs1324913
rs1324913
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C1314691
Disease:
Age at menarche 		G 0.700 GeneticVariation GWASCAT Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. 25231870 2014
dbSNP: rs1886512
rs1886512
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0018803
Disease:
Heart Function Tests 		A 0.700 GeneticVariation GWASCAT Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. 21076409 2010
dbSNP: rs1886512
rs1886512
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0429097
Disease:
QRS complex feature 		0.700 GeneticVariation GWASCAT 52 Genetic Loci Influencing Myocardial Mass. 27659466 2016
dbSNP: rs2025424
rs2025424
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs2025424
rs2025424
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs35185444
rs35185444
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs4454843
rs4454843
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs58598658
rs58598658
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0236664
Disease:
Alcohol-Related Disorders 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs58598658
rs58598658
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C1269683
Disease:
Major Depressive Disorder 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs58598658
rs58598658
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs58598658
rs58598658
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		C 0.700 GeneticVariation GWASCAT Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. 29071344 2017
dbSNP: rs66504755
rs66504755
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0200635
Disease:
Lymphocyte Count measurement 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs728926
rs728926
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0429028
Disease:
QT interval feature (observable entity) 		T 0.700 GeneticVariation GWASCAT Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. 24952745 2014
dbSNP: rs728926
rs728926
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0429097
Disease:
QRS complex feature 		0.700 GeneticVariation GWASCAT 52 Genetic Loci Influencing Myocardial Mass. 27659466 2016
dbSNP: rs7329599
rs7329599
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C1314691
Disease:
Age at menarche 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7335976
rs7335976
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7995668
rs7995668
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C1314691
Disease:
Age at menarche 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7995760
rs7995760
Entrez Id: 11278
Gene Symbol: KLF12
KLF12
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018