TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Disease: Eating Disorders ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1473473
rs1473473
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
CUI: C0013473
Disease:
Eating Disorders 		0.020 GeneticVariation BEFREE The minor allele of rs1473473 (OR = 1.49) was more frequent in impulsive controls, but also in impulsive patients with an ED (OR = 1.83). 23239044 2013
dbSNP: rs1473473
rs1473473
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
CUI: C0013473
Disease:
Eating Disorders 		0.020 GeneticVariation BEFREE A significant effect for the minor C-allele of tryptophan hydroxylase 2 rs1473473 was observed for both AN [odds ratio (OR) = 1.30, 95% CI 1.08-1.57, P < 0.003] and EDs characterized by SV (OR = 1.52, 95% CI 1.28-2.04, P < 0.006). 20946355 2011