RBM45, RNA binding motif protein 45, 129831

N. diseases: 557; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs144910525
rs144910525
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE Rs4774 (missense +1614G/C; G500A) was associated with MS (P = 4.9 x 10(-3)), particularly in DRB1*1501 +individuals (P = 1 x 10(-4)). 20211854 2010
dbSNP: rs1319576996
rs1319576996
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE In conclusion, MOG V142L, or an untested variant in tight-linkage disequilibrium with it, is an independent MS susceptibility-modulating factor in the HLA class I region. 17928868 2008
dbSNP: rs745826707
rs745826707
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.010 GeneticVariation BEFREE SUMO4 M55V variant was associated not only with type 1 diabetes [odds ratio (OR), 1.42; 95% confidence interval (CI), 1.09-1.84; P = 0.0072], but also with increased risk of other autoimmune diseases, AITD (OR, 1.52; 95% CI, 1.14-2.03; P = 0.0041) and RA without amyloidosis (OR, 1.53; 95% CI, 1.65-2.24; P = 0.027), but not primary Sjögren's syndrome. 16735488 2006
dbSNP: rs745826707
rs745826707
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0002726
Disease:
Amyloidosis 		0.010 GeneticVariation BEFREE SUMO4 M55V variant was associated not only with type 1 diabetes [odds ratio (OR), 1.42; 95% confidence interval (CI), 1.09-1.84; P = 0.0072], but also with increased risk of other autoimmune diseases, AITD (OR, 1.52; 95% CI, 1.14-2.03; P = 0.0041) and RA without amyloidosis (OR, 1.53; 95% CI, 1.65-2.24; P = 0.027), but not primary Sjögren's syndrome. 16735488 2006
dbSNP: rs745826707
rs745826707
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0004364
Disease:
Autoimmune Diseases 		0.010 GeneticVariation BEFREE SUMO4 M55V variant was associated not only with type 1 diabetes [odds ratio (OR), 1.42; 95% confidence interval (CI), 1.09-1.84; P = 0.0072], but also with increased risk of other autoimmune diseases, AITD (OR, 1.52; 95% CI, 1.14-2.03; P = 0.0041) and RA without amyloidosis (OR, 1.53; 95% CI, 1.65-2.24; P = 0.027), but not primary Sjögren's syndrome. 16735488 2006
dbSNP: rs745826707
rs745826707
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.010 GeneticVariation BEFREE Furthermore, the association of SUMO4 M55V variant was stronger in type 1 diabetic patients complicated with AITD (OR, 1.62; 95% CI, 1.06-2.47; P = 0.023) and in patients who have neither type 1 diabetes-susceptible class II HLA, DRB1*0405 nor DRB1*0901 (OR, 2.28; 95% CI, 1.34-3.87; P = 0.0018). 16735488 2006
dbSNP: rs745826707
rs745826707
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C3840565
Disease:
Autoimmune thyroid disease (AITD) 		0.010 GeneticVariation BEFREE Furthermore, the association of SUMO4 M55V variant was stronger in type 1 diabetic patients complicated with AITD (OR, 1.62; 95% CI, 1.06-2.47; P = 0.023) and in patients who have neither type 1 diabetes-susceptible class II HLA, DRB1*0405 nor DRB1*0901 (OR, 2.28; 95% CI, 1.34-3.87; P = 0.0018). 16735488 2006