COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Disease: Pain ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4633
rs4633
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.050 GeneticVariation BEFREE Pressure pain was significantly associated with rs6269 and rs4633 following butorphanol. 31806881 2019
dbSNP: rs4633
rs4633
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.050 GeneticVariation BEFREE In the overall sample, rs4633 and rs4680 were significantly associated with morphine use, whereas rs4818 was associated with time-averaged pain scores. 25963335 2016
dbSNP: rs4633
rs4633
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.050 GeneticVariation BEFREE This study was aimed at the evaluation of the relationship between genetic polymorphisms of catechol-O-methyltransferase (COMT) (rs4680:A > G-Val158Met, rs6269:A > G, rs4633:C > T, rs4818:C > G) and pain sensitivity after lumbar discectomy. 24178190 2014
dbSNP: rs4633
rs4633
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.050 GeneticVariation BEFREE No difference was observed in frequencies of rs4633 between PD pain and without pain. 24825955 2014
dbSNP: rs4633
rs4633
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.050 GeneticVariation BEFREE Our results reveal that the alleles of each SNP are not significantly correlated with pain perception except for the rs4633 allele in the 2 Hz TEAS session (P < 0.05). 22253202 2012