COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Disease: Pain ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6269
rs6269
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.030 GeneticVariation BEFREE Pressure pain was significantly associated with rs6269 and rs4633 following butorphanol. 31806881 2019
dbSNP: rs6269
rs6269
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.030 GeneticVariation BEFREE AA genotype of rs165774 could be a significant risk factor for the development of TMD and TMD pain, while AA genotype of rs6269 presents less postoperative chronic TMD pain and acute pain at a dental extraction site. 27792797 2017
dbSNP: rs6269
rs6269
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0030193
Disease:
Pain 		0.030 GeneticVariation BEFREE This study was aimed at the evaluation of the relationship between genetic polymorphisms of catechol-O-methyltransferase (COMT) (rs4680:A > G-Val158Met, rs6269:A > G, rs4633:C > T, rs4818:C > G) and pain sensitivity after lumbar discectomy. 24178190 2014