COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1342715506
rs1342715506
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE In this study, we evaluated the frequency of different polymorphisms related with estrogen metabolism [COMT Val158Met, CYP17 (5'UTR, T27C); HSD17beta1 Gly313Ser and MnSOD Val16Ala] in a breast cancer resistant population, the Xavante Indians, and the frequencies were compared with the ones reported in other populations where breast cancer case-control studies dealing with these polymorphisms have been carried out. 16969494 2006