COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Disease: Major Depressive Disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4818
rs4818
Entrez Id: 1312;100616414
Gene Symbol: COMT;MIR4761
COMT;MIR4761
CUI: C1269683
Disease:
Major Depressive Disorder 		0.010 GeneticVariation BEFREE Although several haplotype combinations showed significance, the combinations of G-T-G-G haplotype for rs6269, rs4633, rs4818 and rs4680 were only present in the MDD group (G-T 4.5%, corrected sim P=0.0001; G-T-G 3.87%, corrected sim P=0.001; G-T-G-G 3.3% corrected sim P=0.0025). 20531207 2010