CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Disease: Coronary heart disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3742264
rs3742264
Entrez Id: 1361;100509894
Gene Symbol: CPB2;CPB2-AS1
CPB2;CPB2-AS1
CUI: C0010068
Disease:
Coronary heart disease 		0.010 GeneticVariation BEFREE In interaction analysis we found statistical evidence of variant-gender interaction conferring risk of CHD and CVD: rs3742264 in the carboxypeptidase B2 gene, p(interaction) = 0.009 for CHD, and rs2774279 in the upstream stimulatory factor 1 gene, p(interaction) = 0.007 for CHD and CVD, showed strong association in women but not in men, while rs2069840 in interleukin 6 gene, p(interaction) = 0.004 for CVD, showed strong association in men but not in women (uncorrected p-values). 18974842 2008