|
rs1926446
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs1926447
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs4942471
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
rs532540191
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs9526137
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs9526138
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs9567617
|
CPB2;CPB2-AS1
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs11574980
|
CPB2;CPB2-AS1
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs11574980
|
CPB2;CPB2-AS1
|
Low density lipoprotein cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs11574980
|
CPB2;CPB2-AS1
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs11574980
|
CPB2;CPB2-AS1
|
Serum HDL cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs1926447
|
CPB2;CPB2-AS1
|
Vertical Talus
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion, TAFI rs3742264, rs2146881, and rs1926447 polymorphisms do not increase the risk of CVT in comparison to healthy controls.
|
29629564 |
2018 |
|
rs1926447
|
CPB2;CPB2-AS1
|
Vertical Talus
|
|
0.030 |
GeneticVariation |
BEFREE |
For genetic factors, CVT risk increased in the presence of factor V Leiden (G1691A) by 2.5-fold (1.9-3.3), protein C deficiency 10.7-fold (3.1-37.7), protein S deficiency 5.7-fold (1.4-22.4), antithrombin deficiency 3.8-fold (1.0-13.8), prothrombin (G20210A) 5.5-fold (4.0-7.27) and TAFI gene variant (C1040T) 1.6-fold (1.0-2.4).
|
30005273 |
2018 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Cardiovascular Diseases
|
|
0.030 |
GeneticVariation |
BEFREE |
Ethnicity subgroup analysis implied that the rs3742264 G>A polymorphism was more likely to lead to the development of cerebrovascular disease in Asians (all P values < 0.05), whereas rs1926447 C>T was associated with cardiovascular disease among Africans (all P values < 0.05).
|
27173177 |
2016 |
|
rs1926447
|
CPB2;CPB2-AS1
|
Vertical Talus
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data indicate that the GTC haplotype for TAFI 505G>A/1040C>T/+1542C>G SNPs increased the risk of CVT in comparison to controls and VTE cases.
|
24252537 |
2014 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Cardiovascular Diseases
|
|
0.030 |
GeneticVariation |
BEFREE |
The present meta-analysis failed to confirm the influence of Ala147Thr and Thr325Ile variants on the susceptibility to CVD.
|
25042727 |
2014 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Cardiovascular Diseases
|
|
0.030 |
GeneticVariation |
BEFREE |
In interaction analysis we found statistical evidence of variant-gender interaction conferring risk of CHD and CVD: rs3742264 in the carboxypeptidase B2 gene, p(interaction) = 0.009 for CHD, and rs2774279 in the upstream stimulatory factor 1 gene, p(interaction) = 0.007 for CHD and CVD, showed strong association in women but not in men, while rs2069840 in interleukin 6 gene, p(interaction) = 0.004 for CVD, showed strong association in men but not in women (uncorrected p-values).
|
18974842 |
2008 |
|
rs1265538677
|
CPB2;CPB2-AS1
|
Breast Carcinoma
|
|
0.020 |
GeneticVariation |
BEFREE |
We tested CPB2 Thr325Ile polymorphism using restriction fragment length polymorphism, (RFLP) technique in healthy and carcinoma breast tissues.
|
29459177 |
2019 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Ischemic stroke
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim was to examine the contribution of the Thr325Ile and Ala147Thr polymorphisms with ST acute myocardial infarction (STEMI) or idiopathic ischemic stroke (IIS) in the young Mexican population.
|
31781299 |
2019 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Vertical Talus
|
|
0.020 |
GeneticVariation |
BEFREE |
We analyzed the association between CVT and TAFI single-nucleotide polymorphisms (rs3742264, rs2146881, and rs1926447) compared to healthy controls.
|
29629564 |
2018 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Ischemic stroke
|
|
0.020 |
GeneticVariation |
BEFREE |
Clinical and genetic variables associated with ischaemic stroke were hypertension (P=.03), tobacco use (P=.02), and the polymorphisms Glu298Asp (genotype: P=.001, allele frequency: P=.001) and C677T (genotype: P=.01); the Ala147Thr, Thr325IIe, 4G/5G, and PLA1/A2 mutations were not associated with ischaemic stroke.
|
29526315 |
2018 |
|
rs1926447
|
CPB2;CPB2-AS1
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
Ethnicity subgroup analysis implied that the rs3742264 G>A polymorphism was more likely to lead to the development of cerebrovascular disease in Asians (all P values < 0.05), whereas rs1926447 C>T was associated with cardiovascular disease among Africans (all P values < 0.05).
|
27173177 |
2016 |
|
rs1265538677
|
CPB2;CPB2-AS1
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
The present meta-analysis failed to confirm the influence of Ala147Thr and Thr325Ile variants on the susceptibility to CVD.
|
25042727 |
2014 |
|
rs1926447
|
CPB2;CPB2-AS1
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
To investigate the associations between two variants Ala147Thr(rs3742264) and Thr325Ile(rs1926447) in TAFI and the risk of CVD.
|
25042727 |
2014 |
|
rs3742264
|
CPB2;CPB2-AS1
|
Vertical Talus
|
|
0.020 |
GeneticVariation |
BEFREE |
Our data indicate that the GTC haplotype for TAFI 505G>A/1040C>T/+1542C>G SNPs increased the risk of CVT in comparison to controls and VTE cases.
|
24252537 |
2014 |