CR2, complement C3d receptor 2, 1380

N. diseases: 123; N. variants: 9
Disease: Lupus Erythematosus ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17615
rs17615
Entrez Id: 1380
Gene Symbol: CR2
CR2
CUI: C0409974
Disease:
Lupus Erythematosus 		0.010 GeneticVariation BEFREE To explore its role in human disease, we analyzed 1,416 individuals from 258 Caucasian and 142 Chinese lupus simplex families and demonstrated that a common three-single-nucleotide polymorphism CR2 haplotype (rs3813946, rs1048971, rs17615) was associated with lupus susceptibility (P = 0.00001) with a 1.54-fold increased risk for the development of disease. 17360460 2007