CR2, complement C3d receptor 2, 1380

N. diseases: 123; N. variants: 9
Disease: Lupus Erythematosus ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3813946
rs3813946
Entrez Id: 1380
Gene Symbol: CR2
CR2
CUI: C0409974
Disease:
Lupus Erythematosus 		0.020 GeneticVariation BEFREE These data confirm the effects of rs3813946 on CR2 transcription, identifying the 5' UTR to be a novel regulatory element for the CR2 gene in which variation may alter gene function and modify the development of lupus. 22673213 2012
dbSNP: rs3813946
rs3813946
Entrez Id: 1380
Gene Symbol: CR2
CR2
CUI: C0409974
Disease:
Lupus Erythematosus 		0.020 GeneticVariation BEFREE Single-nucleotide polymorphism 1 (rs3813946), located in the 5' untranslated region of the CR2 gene, altered transcriptional activity, suggesting a potential mechanism by which CR2 could contribute to the development of lupus. 17360460 2007