MACROD2, mono-ADP ribosylhydrolase 2, 140733

N. diseases: 13; N. variants: 45
Source: CURATED ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4141463
rs4141463
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0004352
Disease:
Autistic Disorder 		0.820 GeneticVariation GWASCAT A genome-wide scan for common alleles affecting risk for autism. 20663923 2010
dbSNP: rs4141463
rs4141463
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0004352
Disease:
Autistic Disorder 		0.820 GeneticVariation GWASDB A genome-wide scan for common alleles affecting risk for autism. 20663923 2010
dbSNP: rs398124654
rs398124654
Entrez Id: 23767;140733
Gene Symbol: FLRT3;MACROD2
FLRT3;MACROD2
CUI: C3808986
Disease:
HYPOGONADOTROPIC HYPOGONADISM 21 WITH OR WITHOUT ANOSMIA 		0.800 GeneticVariation UNIPROT Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. 23643382 2013
dbSNP: rs6110278
rs6110278
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		T 0.800 GeneticVariation GWASDB A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. 19820697 2009
dbSNP: rs6110278
rs6110278
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		T 0.800 GeneticVariation GWASCAT A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. 19820697 2009
dbSNP: rs398124654
rs398124654
Entrez Id: 23767;140733
Gene Symbol: FLRT3;MACROD2
FLRT3;MACROD2
CUI: C3808986
Disease:
HYPOGONADOTROPIC HYPOGONADISM 21 WITH OR WITHOUT ANOSMIA 		C 0.800 CausalMutation CLINVAR
dbSNP: rs1041606
rs1041606
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0017654
Disease:
Glomerular Filtration Rate 		T 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs16996644
rs16996644
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C1305855
Disease:
Body mass index 		C 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs16996657
rs16996657
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs6034019
rs6034019
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs6034146
rs6034146
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0424574
Disease:
Duration of sleep 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. 30846698 2019
dbSNP: rs6079463
rs6079463
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0236773
Disease:
Depressed bipolar I disorder 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
dbSNP: rs6110524
rs6110524
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C4721579
Disease:
Secondary malignant neoplasm of colon and/or rectum 		0.700 GeneticVariation GWASCAT A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer. 30738427 2019
dbSNP: rs6135224
rs6135224
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0017654
Disease:
Glomerular Filtration Rate 		A 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs71190156
rs71190156
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0008074
Disease:
Child Development Disorders, Pervasive 		G 0.700 GeneticVariation GWASCAT Identification of common genetic risk variants for autism spectrum disorder. 30804558 2019
dbSNP: rs73898513
rs73898513
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C1314691
Disease:
Age at menarche 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11908097
rs11908097
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C2985280
Disease:
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs13038351
rs13038351
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C2985280
Disease:
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs1932952
rs1932952
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C2985280
Disease:
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs2423958
rs2423958
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0596887
Disease:
mathematical ability 		C 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs401599
rs401599
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs6043200
rs6043200
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs6043200
rs6043200
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0596887
Disease:
mathematical ability 		G 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs6074798
rs6074798
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0021704
Disease:
Intelligence 		A 0.700 GeneticVariation GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
dbSNP: rs6135385
rs6135385
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018