MAPK14, mitogen-activated protein kinase 14, 1432

N. diseases: 626; N. variants: 7
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C0206172
Disease:
Diabetic Foot
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C4748608
Disease:
NEUROPATHY, CONGENITAL HYPOMYELINATING, 3
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C0442874
Disease:
Neuropathy
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C4722277
Disease:
NEUROPATHY, CONGENITAL HYPOMYELINATING, 2
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs3761980
rs3761980
Entrez Id: 1432;116369
Gene Symbol: MAPK14;SLC26A8
MAPK14;SLC26A8
CUI: C0154754
Disease:
Hereditary and idiopathic neuropathy, unspecified
C 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0206172
Disease:
Diabetic Foot
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0154754
Disease:
Hereditary and idiopathic neuropathy, unspecified
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C4748608
Disease:
NEUROPATHY, CONGENITAL HYPOMYELINATING, 3
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0442874
Disease:
Neuropathy
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C4722277
Disease:
NEUROPATHY, CONGENITAL HYPOMYELINATING, 2
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs80028505
rs80028505
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
T 0.700 GeneticVariation GWASCAT A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. 28672053 2017
dbSNP: rs851023
rs851023
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE The MAPK14 gene SNP rs851023 was associated with PCa and aggressive PCa risk after multiple comparison adjustment. 31667711 2019
dbSNP: rs851023
rs851023
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0600139
Disease:
Prostate carcinoma
0.010 GeneticVariation BEFREE The MAPK14 gene SNP rs851023 was associated with PCa and aggressive PCa risk after multiple comparison adjustment. 31667711 2019
dbSNP: rs7761118
rs7761118
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0949690
Disease:
Spondylarthritis
0.010 GeneticVariation BEFREE Combined analysis identified an association close to genome-wide significance between rs7761118, an intronic SNP of MAPK14, and SpA (p=3.5×10<sup>-7</sup>). 27461236 2017
dbSNP: rs12199654
rs12199654
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0024809
Disease:
Marijuana Abuse
0.010 GeneticVariation BEFREE Of the MAPK14 tSNPs, only rs12199654 had significant genotype effects and genotype × marijuana misuse interaction effects on WM volumes. rs12199654-A homozygotes with marijuana abuse/dependence had significantly smaller total cerebral and lobar WM volumes. 22850347 2013
dbSNP: rs780319980
rs780319980
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C1833219
Disease:
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2B (disorder)
0.010 GeneticVariation BEFREE Four missense mutations in the late endosomal Rab7 GTPase (L129F, K157N, N161T, and V162M) cause the autosomal dominant peripheral neuropathy Charcot-Marie-Tooth type 2B (CMT2B) disease. 23188822 2013
dbSNP: rs3804452
rs3804452
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0036341
Disease:
Schizophrenia
0.010 GeneticVariation BEFREE We also demonstrated that this new variant ss178077483, combined with mir-30e rs7556088 and mir-24-MAPK14 rs3804452, showed a weak gene-gene interaction for schizophrenia risk (P=0.001). 20347265 2010