DisGeNET - a database of gene-disease associations

DAB1, DAB adaptor protein 1, 1600

N. diseases: 81; N. variants: 43

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs12037261

Entrez Id:	1600;105378746
Gene Symbol:	DAB1;LOC105378746

DAB1;LOC105378746

CUI:	C0410702
Disease:

Adolescent idiopathic scoliosis

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs3754260

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0410702
Disease:

Adolescent idiopathic scoliosis

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs4912182

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0410702
Disease:

Adolescent idiopathic scoliosis

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs1202773

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0004352
Disease:

Autistic Disorder

0.010

GeneticVariation

BEFREE

In the total 427 trios, we found significant genetic association between autism and four SNPs in DAB1 (rs12035887 G: p=0.0006; rs3738556 G: p=0.0044; rs1202773 A: p=0.0048; rs12740765 T: p=0.0196).

23333377

2013

dbSNP:

rs12035887

Entrez Id:	1600;112267900
Gene Symbol:	DAB1;LOC112267900

DAB1;LOC112267900

CUI:	C0004352
Disease:

Autistic Disorder

0.010

GeneticVariation

BEFREE

In the total 427 trios, we found significant genetic association between autism and four SNPs in DAB1 (rs12035887 G: p=0.0006; rs3738556 G: p=0.0044; rs1202773 A: p=0.0048; rs12740765 T: p=0.0196).

23333377

2013

dbSNP:

rs12740765

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0004352
Disease:

Autistic Disorder

0.010

GeneticVariation

BEFREE

In the total 427 trios, we found significant genetic association between autism and four SNPs in DAB1 (rs12035887 G: p=0.0006; rs3738556 G: p=0.0044; rs1202773 A: p=0.0048; rs12740765 T: p=0.0196).

23333377

2013

dbSNP:

rs3738556

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0004352
Disease:

Autistic Disorder

0.010

GeneticVariation

BEFREE

In the total 427 trios, we found significant genetic association between autism and four SNPs in DAB1 (rs12035887 G: p=0.0006; rs3738556 G: p=0.0044; rs1202773 A: p=0.0048; rs12740765 T: p=0.0196).

23333377

2013

dbSNP:

rs17425707

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

30239722

2019

dbSNP:

rs76484449

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs542241509

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0883409
Disease:

Cardiac troponin I measurement

0.700

GeneticVariation

GWASCAT

Cardiac Troponin T and Troponin I in the General Population.

31014085

2019

dbSNP:

rs852787

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C1956346
Disease:

Coronary Artery Disease

0.710

GeneticVariation

GWASCAT

How rs852787 and its host gene <i>DAB1</i> are linked to CAD needs further studies.

29472232

2018

dbSNP:

rs852787

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C1956346
Disease:

Coronary Artery Disease

0.710

GeneticVariation

BEFREE

How rs852787 and its host gene <i>DAB1</i> are linked to CAD needs further studies.

29472232

2018

dbSNP:

rs6679454

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C2699541
Disease:

Cytokine Measurement

0.700

GeneticVariation

GWASCAT

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

22610502

2012

dbSNP:

rs269054

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0424574
Disease:

Duration of sleep

0.700

GeneticVariation

GWASCAT

Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.

30846698

2019

dbSNP:

rs540431

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0424574
Disease:

Duration of sleep

0.700

GeneticVariation

GWASCAT

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.

30804565

2019

dbSNP:

rs17579352

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0948008
Disease:

Ischemic stroke

0.700

GeneticVariation

GWASCAT

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.

26674333

2016

dbSNP:

rs10493240

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs10493241

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs10493249

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs1213640

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs12726314

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs1475260

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs7546303

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs973236

Entrez Id:	1600
Gene Symbol:	DAB1

DAB1

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs12086988

Entrez Id:	1600;115209;107984960
Gene Symbol:	DAB1;OMA1;LOC107984960

DAB1;OMA1;LOC107984960

CUI:	C0200635
Disease:

Lymphocyte Count measurement

0.700

GeneticVariation

GWASDB

The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.

22286170

2012