DEFB1, defensin beta 1, 1672

N. diseases: 177; N. variants: 8
Disease: Crohn Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11362
rs11362
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0010346
Disease:
Crohn Disease 		0.010 GeneticVariation BEFREE Subgroup analysis based on disease type showed that: (1) rs11362G>A variant was strongly associated with severe acute pancreatitis (SAP) and chronic gastritis, (2) frequency of rs1800972C>G variant was higher in SAP subgroup, and (3) frequency of rs1799946G>A variant was positively associated with the susceptibility to Crohn's disease (CD) under the allele model and with SAP. 26232989 2015