DEFB1, defensin beta 1, 1672

N. diseases: 177; N. variants: 8
Disease: Periodontitis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800972
rs1800972
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0031099
Disease:
Periodontitis 		0.030 GeneticVariation BEFREE In the overall analysis, there was no significant association between DEFB1 polymorphisms (rs11362, rs1799946 and rs1800972) and periodontitis risk. 31203191 2019
dbSNP: rs1800972
rs1800972
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0031099
Disease:
Periodontitis 		0.030 GeneticVariation BEFREE Significant associations were found between periodontitis and g. -20G>A (rs11362) and g. -44C>G (rs1800972) SNPs in DEFB1 gene as well as p.Ala29Thr (rs1126477) and p.Lys47Arg (rs1126478) SNPs in LTF gene. 28485077 2017
dbSNP: rs1800972
rs1800972
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0031099
Disease:
Periodontitis 		0.030 GeneticVariation BEFREE Case-control studies revealed that the -44 CC genotype of DEFB1 (rs1800972) was associated with periodontitis (OR 2.51), particularly with severe chronic periodontitis (OR 4.15) and with combined severe and moderate chronic periodontitis (OR 4.04). 24276427 2015