DEFB1, defensin beta 1, 1672

N. diseases: 177; N. variants: 8
Disease: Caries (morphologic abnormality) ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11362
rs11362
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0333519
Disease:
Caries (morphologic abnormality) 		0.030 GeneticVariation BEFREE In the Ribeirão Preto group, the allelic and genotypic distributions in the polymorphism rs11362 in DEFB1 were associated with caries experience. 29727722 2018
dbSNP: rs11362
rs11362
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0333519
Disease:
Caries (morphologic abnormality) 		0.030 GeneticVariation BEFREE We analysed 5 DEFB1 polymorphisms, namely 3 functional single-nucleotide polymorphisms (SNPs) at the 5'-untranslated region (UTR), -52G>A (rs1799946), -44C>G (rs1800972), and -20G>A (rs11362), 2 SNPs at the 3'-UTR, c*5G>A (rs1047031) and c*87A>G (rs1800971) SNP located in potential miRNA binding sites, looking for possible correlations with the risk to develop caries in 654 adult subjects from isolated populations of north-eastern Italy. 27846636 2016
dbSNP: rs11362
rs11362
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
CUI: C0333519
Disease:
Caries (morphologic abnormality) 		0.030 GeneticVariation BEFREE The genetic variant rs11362 in DEFB 1 influences caries susceptibility in CL/P children. 23964634 2014