NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Disease: Malignant neoplasm of urinary bladder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800566
rs1800566
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.060 GeneticVariation BEFREE These findings have suggested that the NQO1 Pro187Ser or SULT1A1 Arg213His polymorphism combination with smoking significantly confer susceptibility to BC. 28589969 2017
dbSNP: rs1800566
rs1800566
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.060 GeneticVariation BEFREE Despite some limitations, our meta-analysis provides sufficient evidence that NQO1 Pro187Ser polymorphism may contribute to bladder cancer risk. 25602258 2015
dbSNP: rs1800566
rs1800566
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.060 GeneticVariation BEFREE The odds ratio and 95% confidence interval (CI) were calculated as a measure of the joint effect of NQO1 rs1800566 and iNOS (CCTTT)n polymorphisms on BC risk among cigarette smokers. 24315573 2014
dbSNP: rs1800566
rs1800566
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.060 GeneticVariation BEFREE Association between NAD(P)H:quinone oxidoreductase 1 rs1800566 polymorphism and risk of bladder cancer. 23873104 2013
dbSNP: rs1800566
rs1800566
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.060 GeneticVariation BEFREE The results suggest that NQO1 rs1800566 genetic polymorphism may contribute to bladder cancer development, especially in Asians. 23464456 2012
dbSNP: rs1800566
rs1800566
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.060 GeneticVariation BEFREE Results of this study strongly suggest that the variant allele of NQO1 (Pro187Ser) may affect individual susceptibility to bladder cancer, particularly among smokers, in this ethnic Kashmiri population. 21253823 2011