DLG2, discs large MAGUK scaffold protein 2, 1740

N. diseases: 44; N. variants: 28
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17148090
rs17148090
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0202177
Disease:
Phospholipid measurement 		0.800 GeneticVariation GWASDB Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. 22359512 2012
dbSNP: rs17148090
rs17148090
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0202177
Disease:
Phospholipid measurement 		0.800 GeneticVariation GWASCAT Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. 22359512 2012
dbSNP: rs790356
rs790356
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0027708
Disease:
Nephroblastoma 		G 0.800 GeneticVariation GWASCAT A genome-wide association study identifies susceptibility loci for Wilms tumor. 22544364 2012
dbSNP: rs790356
rs790356
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0027708
Disease:
Nephroblastoma 		G 0.800 GeneticVariation GWASDB A genome-wide association study identifies susceptibility loci for Wilms tumor. 22544364 2012
dbSNP: rs3793947
rs3793947
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0030567
Disease:
Parkinson Disease 		G 0.700 GeneticVariation GWASCAT Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. 25064009 2014
dbSNP: rs286499
rs286499
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		G 0.700 GeneticVariation GWASCAT A genome-wide association study of chronic obstructive pulmonary disease in Hispanics. 25584925 2015
dbSNP: rs1864774
rs1864774
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-wide association study of schizophrenia in Ashkenazi Jews. 26198764 2015
dbSNP: rs17807909
rs17807909
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C2076600
Disease:
Influenza due to Influenza A virus subtype H1N1 		0.700 GeneticVariation GWASCAT No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity. 26379185 2015
dbSNP: rs150829342
rs150829342
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C3548479
Disease:
response to bronchodilator 		G 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs189780858
rs189780858
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C3548479
Disease:
response to bronchodilator 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs192772225
rs192772225
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C3548479
Disease:
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs2155413
rs2155413
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0027092
Disease:
Myopia 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs7479949
rs7479949
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0030567
Disease:
Parkinson Disease 		0.700 GeneticVariation GWASCAT Genome-wide association study of Parkinson's disease in East Asians. 28011712 2017
dbSNP: rs142615018
rs142615018
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs286028
rs286028
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0005910
Disease:
Body Weight 		A 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs3793947
rs3793947
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0030567
Disease:
Parkinson Disease 		G 0.700 GeneticVariation GWASCAT A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. 28892059 2017
dbSNP: rs655484
rs655484
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0338480
Disease:
Common Migraine 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan. 28952330 2018
dbSNP: rs790357
rs790357
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0595921
Disease:
Intraocular pressure disorder 		0.010 GeneticVariation BEFREE The GWAS results revealed a study-wise significant association for IOP at rs790357, which is located within <i>DLG2</i> on chr11q14.1 (p = 1.02×10<sup>-7</sup>). 28966548 2017
dbSNP: rs1864774
rs1864774
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256 2017
dbSNP: rs11233632
rs11233632
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Based on conjunctional FDR < 0.05, we identified 2 loci shared between SCZ and ICV implicating genes FOXO3 (rs10457180) and ITIH4 (rs4687658), 2 loci shared between SCZ and hippocampal volume implicating SLC4A10 (rs4664442) and SPATS2L (rs1653290), and 2 loci shared between SCZ and volume of putamen implicating DCC (rs4632195) and DLG2 (rs11233632). 29136250 2018
dbSNP: rs10466716
rs10466716
Entrez Id: 1740;101929043
Gene Symbol: DLG2;DLG2-AS2
DLG2;DLG2-AS2
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs10466716
rs10466716
Entrez Id: 1740;101929043
Gene Symbol: DLG2;DLG2-AS2
DLG2;DLG2-AS2
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs116875887
rs116875887
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0596887
Disease:
mathematical ability 		C 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs1532312
rs1532312
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs74443493
rs74443493
Entrez Id: 1740
Gene Symbol: DLG2
DLG2
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018