rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells.
15063176
2004
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains.
12575993
2003
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
The human DNA methyltransferases DNMT3A and DNMT3B have two types of promoters with different CpG contents.
12359337
2002
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.
12138111
2002
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites.
11399089
2001
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
10555141
1999
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene.
10647011
1999
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
Cloning, expression and chromosome locations of the human DNMT3 gene family.
10433969
1999
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors.
10325416
1999
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei.
1423634
1992
rs147001633
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Multiple congenital anomalies
T
0.700
CausalMutation
CLINVAR
Predictive motifs derived from cytosine methyltransferases.
2717398
1989