AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs699
rs699
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C4722085
Disease:
Malignant neoplasm of colon and/or rectum
0.010 GeneticVariation BEFREE Our findings suggest that the angiotensin-converting enzyme I/D and angiotensinogen M235T polymorphisms are unlikely to correlate with colorectal cancer. 31642377 2020
dbSNP: rs2067853
rs2067853
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C3898147
Disease:
Neonatal Hypoxic Ischemic Encephalopathy
0.010 GeneticVariation BEFREE To explore the correlation between the rs2067853 polymorphism in angiotensinogen (AGT) gene and neonatal hypoxic-ischemic encephalopathy (HIE). 30915766 2019
dbSNP: rs2067853
rs2067853
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0752304
Disease:
Hypoxic-Ischemic Encephalopathy
0.010 GeneticVariation BEFREE HIE is correlated with maternal factors, fetal growth, uterine environment and labor process, and the rs2067853 polymorphism in AGT gene is associated with HIE. 30915766 2019
dbSNP: rs4762
rs4762
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0038454
Disease:
Cerebrovascular accident
0.010 GeneticVariation BEFREE The M235T and T174M polymorphisms represented an increased risk for stroke in young Mexican individuals. 30521887 2019
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0026691
Disease:
Mucocutaneous Lymph Node Syndrome
0.010 GeneticVariation BEFREE An Angiotensinogen Gene Polymorphism (rs5050) Is Associated with the Risk of Coronary Artery Aneurysm in Southern Chinese Children with Kawasaki Disease. 30719178 2019
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0007222
Disease:
Cardiovascular Diseases
0.010 GeneticVariation BEFREE The results of a genome-wide association study (GWAS) showed that two functional single-nucleotide polymorphisms (SNPs; rs699A>G and rs5050T>G) in the angiotensinogen (AGT) gene were related to cardiovascular disease susceptibility. 30719178 2019
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0026691
Disease:
Mucocutaneous Lymph Node Syndrome
0.010 GeneticVariation BEFREE Our results indicate that the AGT gene polymorphism rs5050T>G may increase the risk of CAA in children with KD, especially those who are younger than 12 months. 30719178 2019
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0010051
Disease:
Coronary Aneurysm
0.010 GeneticVariation BEFREE An Angiotensinogen Gene Polymorphism (rs5050) Is Associated with the Risk of Coronary Artery Aneurysm in Southern Chinese Children with Kawasaki Disease. 30719178 2019
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C1842937
Disease:
AURAL ATRESIA, CONGENITAL
0.010 GeneticVariation BEFREE Our results indicate that the AGT gene polymorphism rs5050T>G may increase the risk of CAA in children with KD, especially those who are younger than 12 months. 30719178 2019
dbSNP: rs699
rs699
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0002895
Disease:
Anemia, Sickle Cell
0.010 GeneticVariation BEFREE AGT M235T gene polymorphism may represent a genetic modifier to vascular morbidities in Egyptian patients with SCD. 30409744 2019
dbSNP: rs699
rs699
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0410158
Disease:
Muscle damage
0.010 GeneticVariation BEFREE Muscle damage was also determined fifteen days after race and angiotensinogen (<i>AGT</i>) Met235Thr, angiotensin-converting enzyme (<i>ACE</i>) I/D, and Bradykinin B2 receptor (<i>BDKRB2</i>) -9/+9 polymorphisms were determined. 31708962 2019
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C4086152
Disease:
Childhood Astrocytoma
0.010 GeneticVariation BEFREE Angiotensinogen rs5050 germline genetic variant as potential biomarker of poor prognosis in astrocytoma. 30383794 2018
dbSNP: rs5050
rs5050
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0004114
Disease:
Astrocytoma
0.010 GeneticVariation BEFREE Angiotensinogen rs5050 germline genetic variant as potential biomarker of poor prognosis in astrocytoma. 30383794 2018
dbSNP: rs2478523
rs2478523
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0272139
Disease:
Erythrocytosis due to low atmospheric pressure
0.010 GeneticVariation BEFREE Additionally, in Tibetan populations, rs2478523 in <i>AGT</i> showed an increased the risk of HAPC. 28881807 2017
dbSNP: rs4762
rs4762
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0272139
Disease:
Erythrocytosis due to low atmospheric pressure
0.010 GeneticVariation BEFREE Using the Chi-squared test and analyses of genetic models, rs2291804, rs2291805, rs3768294, rs3754334, rs6603856, rs6669624, rs11260742, rs13375644 and rs10907223 in <i>EPHA2</i>, and rs699, rs4762 and rs5051 in <i>AGT</i> showed associations with reduced HAPC susceptibility in Han populations. 28881807 2017
dbSNP: rs5051
rs5051
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0272139
Disease:
Erythrocytosis due to low atmospheric pressure
0.010 GeneticVariation BEFREE Using the Chi-squared test and analyses of genetic models, rs2291804, rs2291805, rs3768294, rs3754334, rs6603856, rs6669624, rs11260742, rs13375644 and rs10907223 in <i>EPHA2</i>, and rs699, rs4762 and rs5051 in <i>AGT</i> showed associations with reduced HAPC susceptibility in Han populations. 28881807 2017
dbSNP: rs699
rs699
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0272139
Disease:
Erythrocytosis due to low atmospheric pressure
0.010 GeneticVariation BEFREE Using the Chi-squared test and analyses of genetic models, rs2291804, rs2291805, rs3768294, rs3754334, rs6603856, rs6669624, rs11260742, rs13375644 and rs10907223 in <i>EPHA2</i>, and rs699, rs4762 and rs5051 in <i>AGT</i> showed associations with reduced HAPC susceptibility in Han populations. 28881807 2017
dbSNP: rs699
rs699
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0025517
Disease:
Metabolic Diseases
0.010 GeneticVariation BEFREE The aim of the study was to investigate the association between ACE (I/D) and AGT (M235T) gene polymorphisms and cardiovascular and metabolic disorders in the acromegaly. 28712073 2017
dbSNP: rs699
rs699
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C1861861
Disease:
CARDIOMYOPATHY, FAMILIAL RESTRICTIVE, 1 (disorder)
0.010 GeneticVariation BEFREE Also, 235TT genotype of AGT (M235T) was significantly associated with enhanced risk of the disease phenotype in HCM, DCM, and RCM. 28120210 2017
dbSNP: rs1078499
rs1078499
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension. 27398822 2016
dbSNP: rs11122577
rs11122577
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0085413
Disease:
Polycystic Kidney, Autosomal Dominant
0.010 GeneticVariation BEFREE Significant association between two AGT polymorphisms (rs11122577 and rs4762) and ADPKD was observed. 26482465 2016
dbSNP: rs11122577
rs11122577
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE Hence, the present study was carried out to examine the role of five tagged SNPs viz., g.6147G>A (rs7539020), g.5978A>G (rs2493134); g.6241T>C (rs1078499), g.7781G>T (rs11122577), and g.5855G>A (rs3789678) in the development of hypertension. 27398822 2016
dbSNP: rs3789678
rs3789678
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0085207
Disease:
Gestational Diabetes
0.010 GeneticVariation BEFREE Multiple logistic regression analysis adjusting for maternal age, fetal sex, and gestational diabetes mellitus showed significant associations between angiotensinogen (AGT) rs3789678 T/C and GH (p = 0.0088) and between angiotensin II receptor type 1 (AGTR1) rs275645 G/A and PE (p = 0.0082). 27910864 2016
dbSNP: rs4762
rs4762
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0011847
Disease:
Diabetes
0.010 GeneticVariation BEFREE The univariate analysis revealed that the age, hypertension, family history of diabetes and AGT rs4762 contributed to the progression of CKD in ADPKD. 26482465 2016
dbSNP: rs4762
rs4762
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0085413
Disease:
Polycystic Kidney, Autosomal Dominant
0.010 GeneticVariation BEFREE The results of our study suggest significant association between Thr207Met polymorphism of AGT and CKD progression and acts as an effect modifier of renal disease progression in ADPKD. 26482465 2016