EGF, epidermal growth factor, 1950

N. diseases: 774; N. variants: 33
Disease: Cirrhosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4444903
rs4444903
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C1623038
Disease:
Cirrhosis 		0.020 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) in the epidermal growth factor (EGF, rs4444903), patatin-like phospholipase domain-containing protein 3 (PNPLA3, rs738409) genes, and near the interleukin-28B (IL28B, rs12979860) gene are linked to treatment response, fibrosis, and hepatocellular carcinoma (HCC) in chronic hepatitis C. Whether these SNPs independently or in combination predict clinical deterioration in hepatitis C virus (HCV)-related cirrhosis is unknown. 25504078 2014
dbSNP: rs4444903
rs4444903
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C1623038
Disease:
Cirrhosis 		0.020 GeneticVariation BEFREE In the longitudinal study, the EGF rs4444903 A > G polymorphism was found to be an independent predictor of cirrhosis development (O.R.7·73, 95% C.I.1·21-49·5, P = 0·007). 22236006 2012