EGFR, epidermal growth factor receptor, 1956

N. diseases: 1394; N. variants: 183
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2227983
rs2227983
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE Evaluation of the EGFR polymorphism R497K in two cohorts of neoadjuvantly treated breast cancer patients. 29267323 2017
dbSNP: rs2227983
rs2227983
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE We hypothesized that two EGFR functional polymorphisms, a (CA)n repeat in intron 1, and a single nucleotide polymorphism, R497K, may affect EGFR expression and breast cancer clinical profile. 24629097 2014
dbSNP: rs2227983
rs2227983
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE In this case control study we aimed to analyze the frequency of HER1 R497K (rs 11543848) and HER2 I655V (rs 1136201) Polymorphisms in breast cancer. 23594562 2013
dbSNP: rs2227983
rs2227983
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0678222
Disease:
Breast Carcinoma 		0.040 GeneticVariation BEFREE The aim of the present study was to determine the relationship, if any, between genetic polymorphism in (ESR1) 2014G>A (T594T) and (EGFR) 142285G>A (R521K) with risk of breast cancer and the prognosis in a heterogeneous North Indian population that is known for its diverse ethnicity. 22810499 2012