EPHX1, epoxide hydrolase 1, 2052

N. diseases: 196; N. variants: 5
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0684249
Disease:
Carcinoma of lung
0.080 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0242379
Disease:
Malignant neoplasm of lung
0.080 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung
0.080 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0006826
Disease:
Malignant Neoplasms
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and c</span>ancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0242379
Disease:
Malignant neoplasm of lung
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0684249
Disease:
Carcinoma of lung
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.030 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0006826
Disease:
Malignant Neoplasms
0.030 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.070 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0546837
Disease:
Malignant neoplasm of esophagus
0.060 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0678222
Disease:
Breast Carcinoma
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.040 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0001430
Disease:
Adenoma
0.020 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C4722085
Disease:
Malignant neoplasm of colon and/or rectum
0.020 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0023051
Disease:
Laryngeal Diseases
0.010 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0699885
Disease:
Carcinoma of bladder
0.010 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0005695
Disease:
Bladder Neoplasm
0.010 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs1051740
rs1051740
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder
0.010 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0546837
Disease:
Malignant neoplasm of esophagus
0.070 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.060 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0678222
Disease:
Breast Carcinoma
0.030 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0001430
Disease:
Adenoma
0.020 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251 2011